ea0084ps2-07-64 | Graves’ Disease 1 | ETA2022
Galgoczi Erika
, Katko Monika
, Erdei Annamaria
, Bodor Miklos
, Ujhelyi Bernadett
, Steiber Zita
, Gyory Ferenc
, V. Nagy Endre
Objectives: Glucocorticoids (GCs) are the first line therapy in moderate to severe, active thyroid eye disease (TED). While their beneficial immunosuppressive effects are well known, direct connective tissue effects are less characterized. The accumulation of extracellular matrix component hyaluronan (HA) and increased proliferation rate of fibroblasts are hallmarks connective tissue changes in TED. We examined the effect of methylprednisolone (MP), prednisolone (P), hydrocort...